= Recommendations for intention to treat analysis (Hollis and Campbell, 1999) =

ITT is better regarded as a complete trial strategy for design, conduct and analysis rather than as an approach to analysis alone.

'''Design'''

 * Decide whether the aim is pragmatic or explanatory. For pragmatic trials, intention to treat is essential

 * Justify in advance any inclusion criteria which when violated would merit exclusion from intention to treat analysis

'''Conduct'''

 * Minimise missing response on the primary outcome

 * Follow up subjects who withdraw from treatment

'''Analysis'''

 * Include all randomised subjects in the groups to which they were allocated

 * Investigate the potential effect of missing response

'''Reporting'''

 * Specify that intention to treat analysis has been carried out, explicitly describing the handling of deviations from randomised allocation and missing response

 * Report deviations from randomised allocation and missing response

 * Discuss the potential effect of missing response

 * Base conclusions on the results of intention to treat analysis